Anti-TBC1D24 antibody (12-62 aa) (STJ197981)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TBC24 at the amino acid range 12-62
General Information
| Short Description | Rabbit polyclonal anti-TBC1 domain family member 24 (12-62 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBC1D24 |
| Gene ID | 57465 |
| Uniprot ID | TBC24_HUMAN |
| Immunogen | Synthesized peptide derived from the human TBC24 at the amino acid range 12-62 |
| Immunogen Region | 12-62 aa |
| Specificity | This antibody detects endogenous levels of human TBC24 |
Additional Info
| Function | May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. Involved in the regulation of synaptic vesicle trafficking. |
| Protein Name | Tbc1 Domain Family Member 24 |
| Database Links | Reactome: R-HSA-8854214 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCytoplasmic Vesicle MembranePresynapseMainly Cytoplasmic With Partial Expression At The Plasma MembraneAssociates With Certain Types Of Membrane PhosphoinositidesPreferentially Those Phosphorylated At The D5 Position Of The Inositol Ring Such As Phosphatidylinositol 45-Bisphosphate (Pip2) And Phosphatidylinositol 345-Trisphosphate (Pip3) |
| Alternative Antibody Names | Anti-Tbc1 Domain Family Member 24 antibodyAnti-TBC1D24 antibodyAnti-KIAA1171 antibody |
Information sourced from Uniprot.org