Anti-TAS2R45 antibody (STJ13101810)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human TAS2R45 conjugated to blue carrier protein was used as the antigen. The antibody generated using this antigen is expected to also recognise TAS2R43, TAS2R44 and TAS2R47.
General Information
| Short Description | Rabbit polyclonal anti-TAS2R45 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | TAS2R45Uniprot ID=T2R45_HUMAN" |
| Immunogen | A synthetic peptide from human TAS2R45 conjugated to blue carrier protein was used as the antigen. The antibody generated using this antigen is expected to also recognise TAS2R43, TAS2R44 and TAS2R47. |
| Specificity | Specific for TAS2R45 ( and also TAS2R43, TAS2R44 and TAS2R47. See the Immunogen) |
Additional Info
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Protein Name | Taste Receptor Type 2 Member 45T2r45G-Protein Coupled Receptor 59 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 45 antibodyAnti-T2r45 antibodyAnti-G-Protein Coupled Receptor 59 antibodyAnti-TAS2R45 antibodyAnti-GPR59 antibody |
Information sourced from Uniprot.org