Anti-TAS2R4 antibody (157-171) (STJ72839)

Name: Anti-TAS2R4 antibody (157-171) (STJ72839)
SKU: STJ72839-100
Price: 193.5 GBP
Availability: InStock

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SPECIFICATIONS

ClonalityPolyclonal

HostGoat

ConjugationUnconjugated

IsotypeIgG

STJ72839-100

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Short Description	Goat polyclonal antibody anti-TAS2R4 (157-171) is suitable for use in ELISA research applications.
Applications	Pep-ELISA
Host	Goat
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5 mg/mL
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range	Peptide ELISA: antibody detection limit dilution 1:128000. WB: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol	TAS2R4
Gene ID	50832
Uniprot ID	TA2R4_HUMAN
Accession Number	NP_058640.1
Immunogen Region	157-171
Immunogen Sequence	PELVTTRNNTSFNIS
Specificity	The immunizing peptide represents part of an extracellular domain.

Function	Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
Protein Name	Taste Receptor Type 2 Member 4 T2r4
Database Links	Reactome: R-HSA-418594 Reactome: R-HSA-420499 Reactome: R-HSA-9717207
Cellular Localisation	Membrane Multi-Pass Membrane Protein Cell Projection Cilium Membrane In Airway Epithelial Cells Localizes To Motile Cilia
Alternative Antibody Names	Anti-Taste Receptor Type 2 Member 4 antibody Anti-T2r4 antibody Anti-TAS2R4 antibody

Information sourced from Uniprot.org