Anti-TAS2R14 antibody (250-317) (STJ13100439)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 250-317 of human TAS2R14 conjugated to bluec carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-TAS2R14 (250-317) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | TAS2R14 |
| Gene ID | 50840 |
| Uniprot ID | T2R14_HUMAN |
| Immunogen | A synthetic peptide from aa region 250-317 of human TAS2R14 conjugated to bluec carrier protein was used as the antigen. |
| Immunogen Region | 250-317 |
| Specificity | Specific for TAS2R14. |
Additional Info
| Function | Gustducin-linked G-protein coupled receptor that plays a role in the perception of bitterness. The activity of this receptor stimulates GNAT3, activating the gustducin G-protein pathway. Likely plays a role in sensing the chemical composition of the gastrointestinal content and other extra-oral tissues via the inhibitory G-protein pathways. |
| Protein Name | Taste Receptor Type 2 Member 14T2r14Taste Receptor Family B Member 1Trb1 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499Reactome: R-HSA-9717207 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 14 antibodyAnti-T2r14 antibodyAnti-Taste Receptor Family B Member 1 antibodyAnti-Trb1 antibodyAnti-TAS2R14 antibody |
Information sourced from Uniprot.org