Anti-TARS antibody (1-230) (STJ29073)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TARS (1-230) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TARS1 |
| Gene ID | 6897 |
| Uniprot ID | SYTC_HUMAN |
| Immunogen Region | 1-230 |
| Immunogen Sequence | MFEEKASSPSGKMGGEEKPI GAGEEKQKEGGKKKNKEGSG DGGRAELNPWPEYIYTRLEM YNILKAEHDSILAEKAEKDS KPIKVTLPDGKQVDAESWKT TPYQIACGISQGLADNTVIA KVNNVVWDLDRPLEEDCTLE LLKFEDEEAQAVYWHSSAHI MGEAMERVYGGCLCYGPPIE NGFYYDMYLEEGGVSSNDFS SLEALCKKIIKEKQAFERLE VKKETLLAMF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TARS (NP_689508.3). |
Additional Info
| Post Translational Modifications | ISGylated. |
| Function | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage. |
| Protein Name | Threonine--Trna Ligase 1 - CytoplasmicThreonyl-Trna SynthetaseThrrsThreonyl-Trna Synthetase 1 |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Threonine--Trna Ligase 1 - Cytoplasmic antibodyAnti-Threonyl-Trna Synthetase antibodyAnti-Thrrs antibodyAnti-Threonyl-Trna Synthetase 1 antibodyAnti-TARS1 antibodyAnti-TARS antibody |
Information sourced from Uniprot.org