Anti-TAF1C antibody (70-320) (STJ28842)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TAF1C (70-320) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAF1C |
| Gene ID | 9013 |
| Uniprot ID | TAF1C_HUMAN |
| Immunogen Region | 70-320 |
| Immunogen Sequence | PPLIDPWDPGLTARDLLFRG GYRYRKRPRVVLDVTEQISR FLLDHGDVAFAPLGKLMLEN FKLEGAGSRTKKKTVVSVKK LLQDLGGHQPWGCPWAYLSN RQRRFSILGGPILGTSVASH LAELLHEELVLRWEQLLLDE ACTGGALAWVPGRTPQFGQL VYPAGGAQDRLHFQEVVLTP GDNPQFLGKPGRIQLQGPVR QVVTCTVQGETLLAVRSDYH CAVWKFGKQWQPTLLQAMQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 70-320 of human TAF1C (NP_001230085.1). |
Additional Info
| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
| Protein Name | Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit CRna Polymerase I-Specific Tbp-Associated Factor 110 KdaTafi110Tata Box-Binding Protein-Associated Factor 1cTbp-Associated Factor 1cTranscription Initiation Factor Sl1/Tif-Ib Subunit C |
| Database Links | Reactome: R-HSA-427359Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit C antibodyAnti-Rna Polymerase I-Specific Tbp-Associated Factor 110 Kda antibodyAnti-Tafi110 antibodyAnti-Tata Box-Binding Protein-Associated Factor 1c antibodyAnti-Tbp-Associated Factor 1c antibodyAnti-Transcription Initiation Factor Sl1/Tif-Ib Subunit C antibodyAnti-TAF1C antibody |
Information sourced from Uniprot.org