Anti-TAF15 antibody (579-592 aa) [R04-8A3] (STJA0012025)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human TAF15
General Information
| Short Description | Rabbit monoclonal anti-TAF15 (579-592 aa) for use in WB, IHC-F, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-8A3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4ยฐC short term. Aliquot and store at-20ยฐC long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TAF15 |
| Gene ID | 8148 |
| Uniprot ID | RBP56_HUMAN |
| Immunogen | A synthetic peptide of human TAF15 |
| Immunogen Region | 579-592 aa |
Additional Info
| Tissue Specificity | Ubiquitous. Observed in all fetal and adult tissues. |
| Post Translational Modifications | Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity. ADP-ribosylated during genotoxic stress. |
| Function | RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). |
| Protein Name | Tata-Binding Protein-Associated Factor 2n68 Kda Tata-Binding Protein-Associated FactorTaf(Ii68Tafii68Rna-Binding Protein 56 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | NucleusCytoplasmShuttles From The Nucleus To The Cytoplasm |
| Alternative Antibody Names | Anti-Tata-Binding Protein-Associated Factor 2n antibodyAnti-68 Kda Tata-Binding Protein-Associated Factor antibodyAnti-Taf(Ii68 antibodyAnti-Tafii68 antibodyAnti-Rna-Binding Protein 56 antibodyAnti-TAF15 antibodyAnti-RBP56 antibodyAnti-TAF2N antibody |
Information sourced from Uniprot.org