Anti-TAF15 antibody (351-400 aa) (STJ95895)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TAF15 at the amino acid range 351-400
STJ95895
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General Information

Short DescriptionRabbit polyclonal anti-TATA-binding protein-associated factor 2N68 (351-400 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTAF15
Gene ID8148
Uniprot IDRBP56_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TAF15 at the amino acid range 351-400
Immunogen Region351-400 aa
SpecificityTAF II p68 Polyclonal Antibody detects endogenous levels of TAF II p68 protein.

Additional Info

Post Translational Modifications Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity. ADP-ribosylated during genotoxic stress.
Function RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
Protein Name Tata-Binding Protein-Associated Factor 2n
68 Kda Tata-Binding Protein-Associated Factor
Taf(Ii68
Tafii68
Rna-Binding Protein 56
Database Links Reactome: R-HSA-167161
Reactome: R-HSA-167162
Reactome: R-HSA-167172
Reactome: R-HSA-674695
Reactome: R-HSA-6804756
Reactome: R-HSA-73776
Reactome: R-HSA-73779
Reactome: R-HSA-75953
Reactome: R-HSA-76042
Cellular Localisation Nucleus
Cytoplasm
Shuttles From The Nucleus To The Cytoplasm
Alternative Antibody Names Anti-Tata-Binding Protein-Associated Factor 2n antibody
Anti-68 Kda Tata-Binding Protein-Associated Factor antibody
Anti-Taf(Ii68 antibody
Anti-Tafii68 antibody
Anti-Rna-Binding Protein 56 antibody
Anti-TAF15 antibody
Anti-RBP56 antibody
Anti-TAF2N antibody

Information sourced from Uniprot.org

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