Anti-TAF15 antibody (1-280) (STJ110763)

Name: Anti-TAF15 antibody (1-280) (STJ110763)
SKU: STJ110763
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110763

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Short Description	Rabbit polyclonal TAF15 (1-280) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/IP/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	TAF15
Gene ID	8148
Uniprot ID	RBP56_HUMAN
Immunogen Region	1-280
Immunogen Sequence	MSDSGSYGQSGGEQQSYSTY GNPGSQGYGQASQSYSGYGQ TTDSSYGQNYSGYSSYGQSQ SGYSQSYGGYENQKQSSYSQ QPYNNQGQQQNMESSGSQGG RAPSYDQPDYGQQDSYDQQS GYDQHQGSYDEQSNYDQQHD SYSQNQQSYHSQRENYSHHT QDDRRDVSRYGEDNRGYGGS QGGGRGRGGYDKDGRGPMTG SSGGDRGGFKNFGGHRDYGP RTDADSESDNSDNNTIFVQ
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TAF15 (NP_631961.1).

Tissue Specificity	Ubiquitous. Observed in all fetal and adult tissues.
Post Translational Modifications	Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity. ADP-ribosylated during genotoxic stress.
Function	RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
Protein Name	Tata-Binding Protein-Associated Factor 2n 68 Kda Tata-Binding Protein-Associated Factor Taf(Ii68 Tafii68 Rna-Binding Protein 56
Database Links	Reactome: R-HSA-167161 Reactome: R-HSA-167162 Reactome: R-HSA-167172 Reactome: R-HSA-674695 Reactome: R-HSA-6804756 Reactome: R-HSA-73776 Reactome: R-HSA-73779 Reactome: R-HSA-75953 Reactome: R-HSA-76042
Cellular Localisation	Nucleus Cytoplasm Shuttles From The Nucleus To The Cytoplasm
Alternative Antibody Names	Anti-Tata-Binding Protein-Associated Factor 2n antibody Anti-68 Kda Tata-Binding Protein-Associated Factor antibody Anti-Taf(Ii68 antibody Anti-Tafii68 antibody Anti-Rna-Binding Protein 56 antibody Anti-TAF15 antibody Anti-RBP56 antibody Anti-TAF2N antibody

Information sourced from Uniprot.org