| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TACR1 |
| Gene ID: | 6869 |
| Uniprot ID: | NK1R_HUMAN |
| Immunogen Region: | 300-407 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300-407 of human Neurokinin 1 Receptor (NK1R) (NK1R) (P25103). |
| Immunogen Sequence: | YNPIIYCCLNDRFRLGFKHA FRCCPFISAGDYEGLEMKST RYLQTQGSVYKVSRLETTIS TVVGAHEEEPEDGPKATPSS LDLTSNCSSRSDSKTMTESF SFSSNVLS |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
| Protein Name | Substance-P ReceptorSprNk-1 ReceptorNk-1rTachykinin Receptor 1 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Substance-P Receptor antibodyAnti-Spr antibodyAnti-Nk-1 Receptor antibodyAnti-Nk-1r antibodyAnti-Tachykinin Receptor 1 antibodyAnti-TACR1 antibodyAnti-NK1R antibodyAnti-TAC1R antibody |
Information sourced from Uniprot.org