Anti-MFF antibody (200-300) [S7MR] (STJ11102357)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MFF (200-300) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MFF |
| Gene ID | 56947 |
| Uniprot ID | MFF_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | TPSPQQARVCPPHMLPEDGA NLSSARGILSLIQSSTRRAY QQILDVLDENRRPVLRGGSA AATSNPHHDNVRYGISNIDT TIEGTSDDLTVVDAASLRRQ I |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MFF (Q9GZY8). |
Additional Info
| Tissue Specificity | Highly expressed in heart, kidney, liver, brain, muscle, and stomach. |
| Function | Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. |
| Protein Name | Mitochondrial Fission Factor |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinPeroxisomeCytoplasmic VesicleSecretory VesicleSynaptic Vesicle |
| Alternative Antibody Names | Anti-Mitochondrial Fission Factor antibodyAnti-MFF antibodyAnti-C2orf33 antibodyAnti-AD030 antibodyAnti-AD033 antibodyAnti-GL004 antibody |
Information sourced from Uniprot.org