Host: | Rabbit |
Applications: | WB/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Substance-P receptor (211-260) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:5000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TACR1 |
Gene ID: | 6869 |
Uniprot ID: | NK1R_HUMAN |
Immunogen Region: | 211-260 |
Specificity: | NK-1R Polyclonal Antibody detects endogenous levels of NK-1R protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human NK1R. AA range:211-260 |
Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
Protein Name | Substance-P Receptor Spr Nk-1 Receptor Nk-1r Tachykinin Receptor 1 |
Database Links | Reactome: R-HSA-380095 Reactome: R-HSA-416476 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Substance-P Receptor antibody Anti-Spr antibody Anti-Nk-1 Receptor antibody Anti-Nk-1r antibody Anti-Tachykinin Receptor 1 antibody Anti-TACR1 antibody Anti-NK1R antibody Anti-TAC1R antibody |
Information sourced from Uniprot.org