Anti-T antibody (266-435) [S3MR] (STJ11102243)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Brachyury (266-435) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBXT |
| Gene ID | 6862 |
| Uniprot ID | TBXT_HUMAN |
| Immunogen Region | 266-435 |
| Immunogen Sequence | GALSLPSTHSCDRYPTLRSH RSSPYPSPYAHRNNSPTYSD NSPACLSMLQSHDNWSSLGM PAHPSMLPVSHNASPPTSSS QYPSLWSVSNGAVTPGSQAA AVSNGLGAQFFRGSPAHYTP LTHPVSAPSSSGSPLYEGAA AATDIVDSQYDAAAQGRLIA SWTPVSPPSM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 266-435 of human Brachyury (O15178). |
Additional Info
| Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
| Protein Name | T-Box Transcription Factor TBrachyury ProteinProtein T |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9793380Reactome: R-HSA-9796292Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Transcription Factor T antibodyAnti-Brachyury Protein antibodyAnti-Protein T antibodyAnti-TBXT antibodyAnti-T antibody |
Information sourced from Uniprot.org