| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Synaptotagmin-2 (40-120 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYT2 |
| Gene ID: | 127833 |
| Uniprot ID: | SYT2_HUMAN |
| Immunogen Region: | 40-120 aa |
| Specificity: | SYT2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Post Translational Modifications | Phosphorylation at Thr-199 by WNK1, changes the calcium requirement for SYT2-binding to phospholipid membranes. |
| Function | Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-2Synaptotagmin IiSytii |
| Database Links | Reactome: R-HSA-5250958Reactome: R-HSA-6794361Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Membrane ProteinChromaffin Granule MembraneCytoplasm |
| Alternative Antibody Names | Anti-Synaptotagmin-2 antibodyAnti-Synaptotagmin Ii antibodyAnti-Sytii antibodyAnti-SYT2 antibody |
Information sourced from Uniprot.org
