Anti-SYT12 antibody (95-200) (STJ11102890)

Name: Anti-SYT12 antibody (95-200) (STJ11102890)
SKU: STJ11102890
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102890

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Short Description	Rabbit polyclonal SYT12 (95-200) antibody for use in WB, IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SYT12
Gene ID	91683
Uniprot ID	SYT12_HUMAN
Immunogen Region	95-200
Immunogen Sequence	KGSLSIEDTFESISELGPLE LMGRELDLAPYGTLRKSQSA DSLNSISSVSNTFGQDFTLG QVEVSMEYDTASHTLNVAVM QGKDLLEREEASFESCFMRV SLLPDE
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 95-200 of human SYT12 (NP_001171351.1).

Post Translational Modifications	Phosphorylation of Ser-97 is required for mossy-fiber long-term potentiation.
Function	Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release. Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids. Essential for mossy-fiber long-term potentiation in the hippocampus.
Protein Name	Synaptotagmin-12 Synaptotagmin Xii Sytxii
Database Links	Reactome: R-HSA-6794361
Cellular Localisation	Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Single-Pass Membrane Protein
Alternative Antibody Names	Anti-Synaptotagmin-12 antibody Anti-Synaptotagmin Xii antibody Anti-Sytxii antibody Anti-SYT12 antibody

Information sourced from Uniprot.org