Anti-SYT10 antibody (380-460 aa) (STJ95851)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Synaptotagmin X at the amino acid range 380-460
General Information
| Short Description | Rabbit polyclonal anti-Synaptotagmin-10 (380-460 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SYT10 |
| Gene ID | 341359 |
| Uniprot ID | SYT10_HUMAN |
| Immunogen | Synthesized peptide derived from Synaptotagmin X at the amino acid range 380-460 |
| Immunogen Region | 380-460 aa |
| Specificity | Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein. |
Additional Info
| Function | Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis. Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes.both actions contribute to triggering exocytosis. |
| Protein Name | Synaptotagmin-10Synaptotagmin XSytx |
| Database Links | Reactome: R-HSA-6794361Reactome: R-HSA-9768919 |
| Cellular Localisation | Cytoplasmic VesicleSecretory Vesicle MembraneSingle-Pass Membrane ProteinLocalizes To Neuronal Vesicles Containing Igf1 That Are Not Enriched At SynapsesDoes Not Colocalize With Synaptic Vesicles Or With The Golgi Apparatus |
| Alternative Antibody Names | Anti-Synaptotagmin-10 antibodyAnti-Synaptotagmin X antibodyAnti-Sytx antibodyAnti-SYT10 antibody |
Information sourced from Uniprot.org