Anti-SYT1 antibody (1-60) {Biotin} (STJ503198)

SKU:
STJ503198-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SYT1 (1-60) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.64-0.72 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SYT1
Gene ID: 6857
Uniprot ID: SYT1_HUMAN
Immunogen Region: 1-60
Immunogen: Synthetic peptide taken within amino acid region 1-60 on SYT1 protein.
Tissue Specificity Expressed in melanocytes.
Post Translational Modifications Glycosylated.
Function Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner.these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Protein Name Synaptotagmin-1
Synaptotagmin I
Syti
P65
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-181430
Reactome: R-HSA-210500
Reactome: R-HSA-212676
Reactome: R-HSA-264642
Reactome: R-HSA-5250958
Reactome: R-HSA-5250989
Reactome: R-HSA-6794361
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-888590
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle Membrane
Single-Pass Membrane Protein
Secretory Vesicle
Synaptic Vesicle Membrane
Chromaffin Granule Membrane
Cytoplasm
Alternative Antibody Names Anti-Synaptotagmin-1 antibody
Anti-Synaptotagmin I antibody
Anti-Syti antibody
Anti-P65 antibody
Anti-SYT1 antibody
Anti-SVP65 antibody
Anti-SYT antibody

Information sourced from Uniprot.org

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