Anti-SYP antibody (250-350) {FITC} (STJ503190)

SKU:
STJ503190-100

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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Chicken/Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SYP (250-350) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.60-0.62 µg/µl
Dilution Range: WB: 1:1, 000
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:125
IHC: 1:100
ICC: 1:100
IF: 1:100
CFM: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SYP
Gene ID: 6855
Uniprot ID: SYPH_HUMAN
Immunogen Region: 250-350
Immunogen: Synthetic peptide taken within amino acid region 250-350 on human Synaptophysin protein.
Tissue Specificity Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3. Expressed in the putamen (at protein level).
Post Translational Modifications Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. Phosphorylated by SRC.
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Protein Name Synaptophysin
Major Synaptic Vesicle Protein P38
Database Links Reactome: R-HSA-9662360
Cellular Localisation Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Multi-Pass Membrane Protein
Synapse
Synaptosome
Alternative Antibody Names Anti-Synaptophysin antibody
Anti-Major Synaptic Vesicle Protein P38 antibody
Anti-SYP antibody

Information sourced from Uniprot.org

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