• Immunofluorescence analysis of PC-12 cells using Syntrophin alpha 1 Rabbit polyclonal antibody (STJ11103315) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH/3T3 cells using Syntrophin alpha 1 Rabbit polyclonal antibody (STJ11103315) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using Syntrophin alpha 1 antibody (STJ11103315) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Western blot analysis of extracts of various cell lines, using Syntrophin alpha 1 antibody (STJ11103315) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-Syntrophin alpha 1 antibody (1-90) (STJ11103315)

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STJ11103315

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Syntrophin alpha 1 (1-90) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNTA1
Gene ID: 6640
Uniprot ID: SNTA1_HUMAN
Immunogen Region: 1-90
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human Syntrophin alpha 1 (NP_003089.1).
Immunogen Sequence: MASGRRAPRTGLLELRAGAG SGAGGERWQRVLLSLAEDVL TVSPADGDPGPEPGAPREQE PAQLNGAAEPGAGPPQLPEA LLLQRRRVTV
Tissue Specificity High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
Post Translational Modifications Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD.
Function Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
Protein Name Alpha-1-Syntrophin
59 Kda Dystrophin-Associated Protein A1 Acidic Component 1
Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1
Tacip1
Syntrophin-1
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Cell Junction
Cytoplasm
Cytoskeleton
In Skeletal Muscle
It Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions
Alternative Antibody Names Anti-Alpha-1-Syntrophin antibody
Anti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibody
Anti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibody
Anti-Tacip1 antibody
Anti-Syntrophin-1 antibody
Anti-SNTA1 antibody
Anti-SNT1 antibody

Information sourced from Uniprot.org

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