| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SYNJ1 |
| Gene ID: |
8867 |
| Uniprot ID: |
SYNJ1_HUMAN |
| Immunogen Region: |
100-200 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SYNJ1 (NP_003886.3). |
| Immunogen Sequence: |
GLLGVLRLNLGDTMLHYLVL VTGCMSVGKIQESEVFRVTS TEFISLRIDSSDEDRISEVR KVLNSGNFYFAWSASGISLD LSLNAHRSMQEQTTDNRFFW N |
| Function | Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2. |
| Protein Name | Synaptojanin-1Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1 |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-1855183Reactome: R-HSA-1855204Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Synaptojanin-1 antibodyAnti-Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1 antibodyAnti-SYNJ1 antibodyAnti-KIAA0910 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
