• STJ72672 (0. 03µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SYNGAP1 antibody (1169-1183) (STJ72672)

SKU:
STJ72672-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC/IF
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SYNGAP1 (1169-1183) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.03-0.1µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SYNGAP1
Gene ID: 8831
Uniprot ID: SYGP1_HUMAN
Immunogen Region: 1169-1183
Accession Number: NP_006763.2
Immunogen Sequence: ESAHIEREEYKLKEY
Function Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits.
Protein Name Ras/Rap Gtpase-Activating Protein Syngap
Neuronal Rasgap
Synaptic Ras Gtpase-Activating Protein 1
Synaptic Ras-Gap 1
Database Links Reactome: R-HSA-5658442
Alternative Antibody Names Anti-Ras/Rap Gtpase-Activating Protein Syngap antibody
Anti-Neuronal Rasgap antibody
Anti-Synaptic Ras Gtpase-Activating Protein 1 antibody
Anti-Synaptic Ras-Gap 1 antibody
Anti-SYNGAP1 antibody
Anti-KIAA1938 antibody

Information sourced from Uniprot.org

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