| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-syndecan 1/CD138 (Internal) is suitable for use in ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | ELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SDC1 |
| Gene ID: | 6382 |
| Uniprot ID: | SDC1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002988.3 |
| Specificity: | Reported variants represent identical protein: NP_001006947.1, NP_002988.3. |
| Immunogen Sequence: | REQEATPRPRETTQ |
| Post Translational Modifications | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway. |
| Protein Name | Syndecan-1Synd1Cd Antigen Cd138 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022928Reactome: R-HSA-2024096Reactome: R-HSA-202733Reactome: R-HSA-3000170Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3656237Reactome: R-HSA-3656253Reactome: R-HSA-4420332Reactome: R-HSA-449836Reactome: R-HSA-9694614Reactome: R-HSA-975634 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedExtracellular ExosomeShedding Of The Ectodomain Produces A Soluble Form |
| Alternative Antibody Names | Anti-Syndecan-1 antibodyAnti-Synd1 antibodyAnti-Cd Antigen Cd138 antibodyAnti-SDC1 antibodyAnti-SDC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-CD138 antibody [B-A38] (STJ16100321)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/149039/346655/STJ16100321_1__20732.1681998731.jpg?c=1 "Anti-CD138 antibody [B-A38] (STJ16100321)")