| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Synaptotagmin-2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.1-0.3µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
SYT2 |
| Gene ID: |
127833 |
| Uniprot ID: |
SYT2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_796376.2 |
| Specificity: |
Reported variants represent identical protein: NP_001129976.1, NP_796376.2 |
| Immunogen Sequence: |
KPEEEVDALLGKNK |
| Post Translational Modifications | Phosphorylation at Thr-199 by WNK1, changes the calcium requirement for SYT2-binding to phospholipid membranes. |
| Function | Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-2Synaptotagmin IiSytii |
| Database Links | Reactome: R-HSA-5250958Reactome: R-HSA-6794361Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneSingle-Pass Membrane ProteinChromaffin Granule MembraneCytoplasm |
| Alternative Antibody Names | Anti-Synaptotagmin-2 antibodyAnti-Synaptotagmin Ii antibodyAnti-Sytii antibodyAnti-SYT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
