Anti-Synaptophysin antibody [SP15] (STJ16101945)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenCrude human synaptic immunoprecipitate
General Information
| Short Description | Mouse monoclonal anti-Synaptophysin for use in ELISA, IHC-P and WB in Human, Hamster and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC-P/WB |
| Host | Mouse |
| Reactivity | Human/Hamster/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SP15 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Formulation | PBS with <0.1% sodium azide |
| Storage Instruction | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
Target Information
| Gene Symbol | SYP |
| Gene ID | 6855 |
| Uniprot ID | SYPH_HUMAN |
| Immunogen | Crude human synaptic immunoprecipitate |
Additional Info
| Tissue Specificity | Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3. Expressed in the putamen (at protein level). |
| Post Translational Modifications | Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. Phosphorylated by SRC. |
| Function | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. |
| Protein Name | SynaptophysinMajor Synaptic Vesicle Protein P38 |
| Database Links | Reactome: R-HSA-9662360 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Synaptophysin antibodyAnti-Major Synaptic Vesicle Protein P38 antibodyAnti-SYP antibody |
Information sourced from Uniprot.org