Anti-Synapsin 2 antibody [R01-7Y2] (STJA0036906)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Synapsin II
General Information
| Short Description | Rabbit monoclonal anti-Synapsin 2 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-7Y2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SYN2 |
| Gene ID | 6854 |
| Uniprot ID | SYN2_HUMAN |
| Immunogen | A synthesized peptide derived from human Synapsin II |
Additional Info
| Tissue Specificity | Central and peripheral nervous systems. |
| Post Translational Modifications | Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons. |
| Function | Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. |
| Protein Name | Synapsin-2Synapsin Ii |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-212676 |
| Cellular Localisation | Synapse |
| Alternative Antibody Names | Anti-Synapsin-2 antibodyAnti-Synapsin Ii antibodyAnti-SYN2 antibody |
Information sourced from Uniprot.org