• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synapsin1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from NIH/3T3 cells, treated with Nocodazole 1ug/ml 16h, using Synapsin1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of NIH-3T3 cells using Synapsin I Polyclonal Antibody

Anti-SYN1 antibody (26-75 aa) (STJ95847)

SKU:
STJ95847

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Synapsin-1 (26-75 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYN1
Gene ID: 6853
Uniprot ID: SYN1_HUMAN
Immunogen Region: 26-75 aa
Specificity: Synapsin I Polyclonal Antibody detects endogenous levels of Synapsin I protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Synapsin1 at the amino acid range 26-75
Function Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Protein Name Synapsin-1
Brain Protein 4.1
Synapsin I
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-212676
Reactome: R-HSA-9662360
Cellular Localisation Synapse
Golgi Apparatus
Presynapse
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle
Dissociates From Synaptic Vesicles And Redistributes Into The Axon During Action Potential Firing
In A Step That Precedes Fusion Of Vesicles With The Plasma Membrane
Reclusters To Presynapses After The Cessation Of Synaptic Activity
Alternative Antibody Names Anti-Synapsin-1 antibody
Anti-Brain Protein 4.1 antibody
Anti-Synapsin I antibody
Anti-SYN1 antibody

Information sourced from Uniprot.org

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