Anti-SYMPK antibody (STJA0009292)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Symplekin
General Information
| Short Description | Rabbit polyclonal anti-Symplekin for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SYMPK |
| Gene ID | 8189 |
| Uniprot ID | SYMPK_HUMAN |
| Immunogen | Synthesized peptide derived from human Symplekin |
| Specificity | This antibody detects endogenous levels of Symplekin at Human |
Additional Info
| Function | Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity. |
| Protein Name | Symplekin |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionTight JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideNucleusNucleoplasmCytoplasmic Face Of Adhesion Plaques (Major) And Nucleoplasm (Minor) (In Cells With Tj)Nucleoplasm (In Cells Without Tj)Nuclear Bodies Of Heat-Stressed CellsColocalizes With Hsf1 In Nuclear Stress Bodies Upon Heat Shock |
| Alternative Antibody Names | Anti-Symplekin antibodyAnti-SYMPK antibodyAnti-SPK antibody |
Information sourced from Uniprot.org