Western blot analysis using SCP-3 monoclonal antibody against mouse pancreas lysate.

Anti-SYCP3 antibody (STJ98548)

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STJ98548
£149.00 - £360.00
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Short Description :Mouse monoclonal anti-Synaptonemal complex protein 3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Affinity purification
Dilution Range:WB 1:1000-1:2000
Formulation:Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SYCP3
Gene ID:50511
Uniprot ID:SYCP3_HUMAN
Immunogen:Purified recombinant human SCP-3 protein fragments expressed in E.coli.
Specificity:SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.
Post Translational Modifications Phosphorylated.
Function Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2.
Protein Name Synaptonemal Complex Protein 3
Scp-3
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
Centromere
It Is Present In Early Unpaired Cores
In The Lateral Domains Of The Synaptonemal Complex And In The Chromosome Cores When They Separate At Diplotene
It Is Found Axial To The Metaphase I Chromosomes And In Association With Pairs Of Sister Centromeres
The Centromere-Associated Protein Becomes Dissociated From The Centromeres At Anaphase Ii And Is Not Found In Mitotic Metaphase Centromeres
Alternative Antibody Names Anti-Synaptonemal Complex Protein 3 antibody
Anti-Scp-3 antibody
Anti-SYCP3 antibody
Anti-SCP3 antibody

Information sourced from Uniprot.org

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