| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SYCP2 (1231-1530) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SYCP2 |
| Gene ID: |
10388 |
| Uniprot ID: |
SYCP2_HUMAN |
| Immunogen Region: |
1231-1530 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1231-1530 of human SYCP2 (NP_055073.2). |
| Immunogen Sequence: |
EIESPHINENYIQSKREESH LASSLSKSSEGREKTWFDMP CDATHVSGPTQHLSRKRIYI EDNLSNSNEVEMEEKGERRA NLLPKKLCKIEDADHHIHKM SESVSSLSTNDFSIPWETWQ NEFAGIEMTYETYERLNSEF KRRNNIRHKMLSYFTTQSWK TAQQHLRTMNHQSQDSRIKK LDKFQFIIIEELENFEKDSQ SLKDLEKEFVDFWEKIFQKF SAYQKSEQQRLHLLKTSLA |
| Post Translational Modifications | Phosphorylated. |
| Function | Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements. |
| Protein Name | Synaptonemal Complex Protein 2Scp-2Synaptonemal Complex Lateral Element ProteinHsscp2 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeIn Axial/Lateral Elements Of The Tripartite Segments Of Synaptonemal Complexes |
| Alternative Antibody Names | Anti-Synaptonemal Complex Protein 2 antibodyAnti-Scp-2 antibodyAnti-Synaptonemal Complex Lateral Element Protein antibodyAnti-Hsscp2 antibodyAnti-SYCP2 antibodyAnti-SCP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
