Anti-SUPT20H antibody (231-280 aa) (STJ98659)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A at the amino acid range 231-280
General Information
| Short Description | Rabbit polyclonal anti-Transcription factor SPT20 homolog (231-280 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SUPT20H |
| Gene ID | 55578 |
| Uniprot ID | SP20H_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A at the amino acid range 231-280 |
| Immunogen Region | 231-280 aa |
| Specificity | The antibody detects endogenous FAM48A protein |
Additional Info
| Function | Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy. |
| Protein Name | Transcription Factor Spt20 HomologP38-Interacting ProteinP38ip |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Spt20 Homolog antibodyAnti-P38-Interacting Protein antibodyAnti-P38ip antibodyAnti-SUPT20H antibodyAnti-C13orf19 antibodyAnti-FAM48A antibodyAnti-FP757 antibody |
Information sourced from Uniprot.org