| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transcription factor SPT20 homolog (231-280 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SUPT20H |
| Gene ID: | 55578 |
| Uniprot ID: | SP20H_HUMAN |
| Immunogen Region: | 231-280 aa |
| Specificity: | The antibody detects endogenous FAM48A protein |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A at the amino acid range 231-280 |
| Function | Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy. |
| Protein Name | Transcription Factor Spt20 HomologP38-Interacting ProteinP38ip |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Spt20 Homolog antibodyAnti-P38-Interacting Protein antibodyAnti-P38ip antibodyAnti-SUPT20H antibodyAnti-C13orf19 antibodyAnti-FAM48A antibodyAnti-FP757 antibody |
Information sourced from Uniprot.org