Anti-Superoxide Dismutase 3 antibody [R08-4J3] (STJA0036531)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Superoxide Dismutase 3
STJA0036531
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General Information

Short DescriptionRabbit monoclonal anti-Superoxide Dismutase 3 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR08-4J3
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity Chromatography
Dilution RangeWB 1:500-1:1000
IHC 1:50-1:100
FormulationRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolSOD3
Gene ID6649
Uniprot IDSODE_HUMAN
ImmunogenA synthesized peptide derived from human Superoxide Dismutase 3

Additional Info

Tissue Specificity Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Function Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Protein Name Extracellular Superoxide Dismutase Cu-Zn
Ec-Sod
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-9818027
Cellular Localisation Secreted
Extracellular Space
Golgi Apparatus
Trans-Golgi Network
99% Of Ec-Sod Is Anchored To Heparan Sulfate Proteoglycans In The Tissue Interstitium
And 1% Is Located In The Vasculature In Equilibrium Between The Plasma And The Endothelium
Alternative Antibody Names Anti-Extracellular Superoxide Dismutase Cu-Zn antibody
Anti-Ec-Sod antibody
Anti-SOD3 antibody

Information sourced from Uniprot.org

Citations

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