Anti-SUMO4 antibody (N-Term) (STJ13102046)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the n-terminal of human SUMO4 (Small ubiquitin-related modifier4) conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SUMO4 (N-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SUMO4 |
| Gene ID | 387082 |
| Uniprot ID | SUMO4_HUMAN |
| Immunogen | A synthetic peptide from the n-terminal of human SUMO4 (Small ubiquitin-related modifier4) conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for SUMO4. |
Additional Info
| Post Translational Modifications | In contrast to SUMO1, SUMO2 and SUMO3, seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90. This may impair processing to mature form and conjugation to substrates. |
| Function | Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. |
| Protein Name | Small Ubiquitin-Related Modifier 4Sumo-4Small Ubiquitin-Like Protein 4 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Small Ubiquitin-Related Modifier 4 antibodyAnti-Sumo-4 antibodyAnti-Small Ubiquitin-Like Protein 4 antibodyAnti-SUMO4 antibodyAnti-SMT3H4 antibody |
Information sourced from Uniprot.org