Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SUMF2 (45-320) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SUMF2 |
Gene ID: |
25870 |
Uniprot ID: |
SUMF2_HUMAN |
Immunogen Region: |
45-320 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 45-320 of human SUMF2 (NP_056226.2). |
Immunogen Sequence: |
QATSMVQLQGGRFLMGTNSP DSRDGEGPVREATVKPFAID IFPVTNKDFRDFVREKKYRT EAEMFGWSFVFEDFVSDELR NKATQPMKSVLWWLPVEKAF WRQPAGPGSGIRERLEHPVL HVSWNDARAYCAWRGKRLPT EEEWEFAARGGLKGQVYPWG NWFQPNRTNLWQGKFPKGDK AEDGFHGVSPVNAFPAQNNY GLYDLLGNVWEWTASPYQAA EQDMRVLRGASWIDTADGS |
Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta. |
Function | Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. |
Protein Name | Inactive C-Alpha-Formylglycine-Generating Enzyme 2Paralog Of Formylglycine-Generating EnzymePfgeSulfatase-Modifying Factor 2 |
Database Links | Reactome: R-HSA-1660662Reactome: R-HSA-1663150 |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative Antibody Names | Anti-Inactive C-Alpha-Formylglycine-Generating Enzyme 2 antibodyAnti-Paralog Of Formylglycine-Generating Enzyme antibodyAnti-Pfge antibodyAnti-Sulfatase-Modifying Factor 2 antibodyAnti-SUMF2 antibodyAnti-PSEC0171 antibodyAnti-UNQ1968 antibodyAnti-PRO4500 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance