• Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-SULT2A1 antibody (STJ193153)

SKU:
STJ193153

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Sulfotransferase 2A1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SULT2A1
Gene ID: 6822
Uniprot ID: ST2A1_HUMAN
Specificity: This antibody detects endogenous levels of human ST2A1
Immunogen: Synthesized peptide derived from the human ST2A1
Post Translational Modifications The N-terminus is blocked.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols.
Protein Name Sulfotransferase 2a1
St2a1
Bile Salt Sulfotransferase
Dehydroepiandrosterone Sulfotransferase
Dhea-St
Dhea-St8
Hydroxysteroid Sulfotransferase
Hst
St2
Sult2a3
Database Links Reactome: R-HSA-156584
Reactome: R-HSA-1989781
Reactome: R-HSA-9753281
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Sulfotransferase 2a1 antibody
Anti-St2a1 antibody
Anti-Bile Salt Sulfotransferase antibody
Anti-Dehydroepiandrosterone Sulfotransferase antibody
Anti-Dhea-St antibody
Anti-Dhea-St8 antibody
Anti-Hydroxysteroid Sulfotransferase antibody
Anti-Hst antibody
Anti-St2 antibody
Anti-Sult2a3 antibody
Anti-SULT2A1 antibody
Anti-HST antibody
Anti-STD antibody

Information sourced from Uniprot.org

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