Anti-SULT1C4 antibody (1-95) (STJ117628)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SULT1C4 (1-95) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT1C4 |
| Gene ID | 27233 |
| Uniprot ID | ST1C4_HUMAN |
| Immunogen Region | 1-95 |
| Immunogen Sequence | MALHDMEDFTFDGTKRLSVN YVKGILQPTDTCDIWDKIWN FQAKPDDLLISTYPKAGTTW TQEIVELIQNEGDVEKSKRA PTHQRFPFLEMKIPS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SULT1C4 (NP_006579.2). |
Additional Info
| Tissue Specificity | Expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal cord. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Can also sulfonate estrogenic compounds, however, the dietary flavonoids (phytoestrogen) and environmental estrogens, like bisphenol A are better substrates than 17beta-estradiol (E2). Mediates the sulfation of doxorubicin and its analog epirubicin, two antitumor anthracyclines. |
| Protein Name | Sulfotransferase 1c4St1c4Sulfotransferase 1c2Sult1c#2 |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Sulfotransferase 1c4 antibodyAnti-St1c4 antibodyAnti-Sulfotransferase 1c2 antibodyAnti-Sult1c#2 antibodyAnti-SULT1C4 antibodyAnti-SULT1C2 antibody |
Information sourced from Uniprot.org