Anti-SULT1B1 antibody (223-273 aa) (STJ196075)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ST1B1 at the amino acid range 223-273
General Information
| Short Description | Rabbit polyclonal anti-Sulfotransferase 1B1 (223-273 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT1B1 |
| Gene ID | 27284 |
| Uniprot ID | ST1B1_HUMAN |
| Immunogen | Synthesized peptide derived from the human ST1B1 at the amino acid range 223-273 |
| Immunogen Region | 223-273 aa |
| Specificity | This antibody detects endogenous levels of ST1B1 at Human/Mouse/Rat |
Additional Info
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system. |
| Protein Name | Sulfotransferase 1b1St1b1Sulfotransferase 1b2Sulfotransferase Family Cytosolic 1b Member 1Thyroid Hormone Sulfotransferase |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfotransferase 1b1 antibodyAnti-St1b1 antibodyAnti-Sulfotransferase 1b2 antibodyAnti-Sulfotransferase Family Cytosolic 1b Member 1 antibodyAnti-Thyroid Hormone Sulfotransferase antibodyAnti-SULT1B1 antibodyAnti-ST1B2 antibodyAnti-SULT1B2 antibody |
Information sourced from Uniprot.org