Anti-STXBP2 antibody (1-280) (STJ114385)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal STXBP2 (1-280) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STXBP2 |
| Gene ID | 6813 |
| Uniprot ID | STXB2_HUMAN |
| Immunogen Region | 1-280 |
| Immunogen Sequence | MAPSGLKAVVGEKILSGVIR SVKKDGEWKVLIMDHPSMRI LSSCCKMSDILAEGITIVED INKRREPIPSLEAIYLLSPT EKALIKDFQGTPTFTYKAAH IFFTDTCPEPLFSELGRSRL AKVVKTLKEIHLAFLPYEAQ VFSLDAPHSTYNLYCPFRAE ERTRQLEVLAQQIATLCATL QEYPAIRYRKGPEDTAQLAH AVLAKLNAFKADTPSLGEGP EKTRSQLLIMDRAADPVSP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1). |
Additional Info
| Tissue Specificity | Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes. |
| Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. |
| Protein Name | Syntaxin-Binding Protein 2Protein Unc-18 Homolog 2Unc18-2Protein Unc-18 Homolog BUnc-18b |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-449836 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 2 antibodyAnti-Protein Unc-18 Homolog 2 antibodyAnti-Unc18-2 antibodyAnti-Protein Unc-18 Homolog B antibodyAnti-Unc-18b antibodyAnti-STXBP2 antibodyAnti-UNC18B antibody |
Information sourced from Uniprot.org