Anti-STX8 antibody (1-215) (STJ112090)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal STX8 (1-215) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STX8 |
| Gene ID | 9482 |
| Uniprot ID | STX8_HUMAN |
| Immunogen Region | 1-215 |
| Immunogen Sequence | MAPDPWFSTYDSTCQIAQEI AEKIQQRNQYERKGEKAPKL TVTIRALLQNLKEKIALLKD LLLRAVSTHQITQLEGDRRQ NLLDDLVTRERLLLASFKNE GAEPDLIRSSLMSEEAKRGA PNPWLFEEPEETRGLGFDEI RQQQQKIIQEQDAGLDALSS IISRQKQMGQEIGNELDEQN EIIDDLANLVENTDEKLRNE TRRVNMVDRKSASCG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human STX8 (NP_004844.1). |
Additional Info
| Tissue Specificity | Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Post Translational Modifications | Ubiquitinated by HECTD3. |
| Function | Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. |
| Protein Name | Syntaxin-8 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type Iv Membrane ProteinPreferentially Associated With The Early EndosomeTo A Lesser ExtentAlso Present In Late EndosomeThe Plasma Membrane And Coated Pits |
| Alternative Antibody Names | Anti-Syntaxin-8 antibodyAnti-STX8 antibody |
Information sourced from Uniprot.org