Anti-STRN antibody (581-780) (STJ110045)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal STRN (581-780) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STRN |
| Gene ID | 6801 |
| Uniprot ID | STRN_HUMAN |
| Immunogen Region | 581-780 |
| Immunogen Sequence | HQRLLSCSADGTLRLWNTTE VAPALSVFNDTKELGIPASV DLVSSDPSHMVASFSKGYTS IFNMETQQRILTLESNVDTT ANSSCQINRVISHPTLPISI TAHEDRHIKFYDNNTGKLIH SMVAHLEAVTSLAVDPNGLY LMSGSHDCSIRLWNLESKTC IQEFTAHRKKFEESIHDVAF HPSKCYIASAGADALAKVFV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 581-780 of human STRN (NP_003153.2). |
Additional Info
| Tissue Specificity | Preferentially expressed in brain. |
| Function | Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (Probable). |
| Protein Name | Striatin |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-6811558Reactome: R-HSA-9009391Reactome: R-HSA-9673766Reactome: R-HSA-9700645Reactome: R-HSA-9725370 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinCell ProjectionDendritic SpineCttnbp2-Binding May Regulate Dendritic Spine Distribution |
| Alternative Antibody Names | Anti-Striatin antibodyAnti-STRN antibody |
Information sourced from Uniprot.org