Anti-Stra8 antibody [PT1391R] (STJA0040025)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog for use in WB, IHC, IF, IP and ELISA in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/IP/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT1391R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | IHC 1:200-1:1000WB 1:2000-1:10000IF 1:200-1:1000ELISA 1:5000-1:20000IP 1:50-1:200 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STRA8 |
| Gene ID | 346673 |
| Uniprot ID | STRA8_HUMAN |
| Specificity | Endogenous |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis. |
| Protein Name | Stimulated By Retinoic Acid Gene 8 Protein Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between Nucleus And CytoplasmNuclear Export Is Xpo1-Dependent |
| Alternative Antibody Names | Anti-Stimulated By Retinoic Acid Gene 8 Protein Homolog antibodyAnti-STRA8 antibody |
Information sourced from Uniprot.org