Anti-STK33 antibody [R03-9B3] (STJA0034895)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human STK33
General Information
| Short Description | Rabbit monoclonal anti-STK33 for use in WB, IHC-F, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-9B3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | STK33 |
| Gene ID | 65975 |
| Uniprot ID | STK33_HUMAN |
| Immunogen | Recombinant protein of human STK33 |
Additional Info
| Tissue Specificity | Highly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were observed in the following tissues: amygdala, aorta, esophagus, colon ascending, colon transverse, skeletal muscle, spleen, peripheral blood leukocyte, lymph node, bone marrow, placenta, prostate, liver, salivary gland, mammary gland, some tumor cell lines, fetal brain, fetal liver, fetal spleen and fetal thymus. No signal at all was detectable in RNA from tissues of the nervous system. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Serine/threonine protein kinase required for spermatid differentiation and male fertility. Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 and AKAP4. Also phosphorylates vimentin/VIM, thereby regulating the dynamic behavior of the intermediate filament cytoskeleton. |
| Protein Name | Serine/Threonine-Protein Kinase 33 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonPerinuclear RegionColocalizes With The Caudal End Of The ManchetteA Transient Structure That Guides Tail Elongation In Elongating Spermatids |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase 33 antibodyAnti-STK33 antibody |
Information sourced from Uniprot.org