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Anti-STAT5A antibody (C-Term) (STJ72748)

STJ72748 (0. 3µg/ml) staining of K562 (A) , Molt4 (B) and NIH3T3 (C) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
STJ72748 (8µg/ml) staining of paraffin embedded Human Tonsil. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
STJ72748 Negative Control showing staining of paraffin embedded Human Tonsil, with no primary antibody.

Anti-STAT5A antibody (C-Term) (STJ72748)

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STJ72748-100

£303.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-STAT5A (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.3-1µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	STAT5A
Gene ID:	6776
Uniprot ID:	STA5A_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_003143.2
Specificity:	This antibody is not expected to cross-react with STAT5B.
Immunogen Sequence:	DSRLSPPAGLFTSAR

Function	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Protein Name	Signal Transducer And Activator Of Transcription 5a
Database Links	Reactome: R-HSA-1170546 Reactome: R-HSA-1251985 Reactome: R-HSA-1266695 Reactome: R-HSA-1433557 Reactome: R-HSA-1839117 Reactome: R-HSA-186763 Reactome: R-HSA-2586552 Reactome: R-HSA-512988 Reactome: R-HSA-8854691 Reactome: R-HSA-8983432 Reactome: R-HSA-8985947 Reactome: R-HSA-9020558 Reactome: R-HSA-9020958 Reactome: R-HSA-9027283 Reactome: R-HSA-9645135 Reactome: R-HSA-9670439 Reactome: R-HSA-9674555 Reactome: R-HSA-9702518 Reactome: R-HSA-9703465 Reactome: R-HSA-9705462 Reactome: R-HSA-9725371 Reactome: R-HSA-982772
Cellular Localisation	Cytoplasm Nucleus Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names	Anti-Signal Transducer And Activator Of Transcription 5a antibody Anti-STAT5A antibody Anti-STAT5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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