Anti-Stargazin antibody (STJ13100088)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from mouse CACNG2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat.
General Information
| Short Description | Rabbit polyclonal anti-Stargazin for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:500 to 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CACNG2 |
| Gene ID | 10369 |
| Uniprot ID | CCG2_HUMAN |
| Immunogen | A synthetic peptide from mouse CACNG2 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat. |
| Specificity | Specific for CACNG2. |
Additional Info
| Post Translational Modifications | Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4. |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-2 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-2 SubunitTransmembrane Ampar Regulatory Protein Gamma-2Tarp Gamma-2 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-399719Reactome: R-HSA-5682910 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-2 antibodyAnti-Tarp Gamma-2 antibodyAnti-CACNG2 antibody |
Information sourced from Uniprot.org