| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Mouse/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Stap2-Mouse (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 50kDa band observed in Mouse fetal Brain and fetal Stomach lysates (calculated MW of 45.8kDa according to NP_666046.1). This molecular weight is routinely observed by other sour |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Immunogen Region: | C-Term |
| Accession Number: | NP_666046.1 |
| Immunogen Sequence: | EEKLQKRRALEH |
| Post Translational Modifications | Phosphorylated on tyrosine. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. |
| Function | Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. |
| Protein Name | Signal-Transducing Adaptor Protein 2Stap-2 |
| Database Links | Reactome: R-MMU-8849474 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinThe Translocation To The Membranes Occurs In Response To Egf When The Protein Is Overexpressed In Fibroblastic Cells |
| Alternative Antibody Names | Anti-Signal-Transducing Adaptor Protein 2 antibodyAnti-Stap-2 antibodyAnti-Stap2 antibody |
Information sourced from Uniprot.org
