Anti-STAP2 antibody (STJ191823)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Signal-transducing adaptor protein 2 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STAP2 |
| Gene ID | 55620 |
| Uniprot ID | STAP2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | STAP2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC. |
| Function | Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. |
| Protein Name | Signal-Transducing Adaptor Protein 2Stap-2Breast Tumor Kinase SubstrateBrk Substrate |
| Database Links | Reactome: R-HSA-8849474Reactome: R-HSA-9707564 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Signal-Transducing Adaptor Protein 2 antibodyAnti-Stap-2 antibodyAnti-Breast Tumor Kinase Substrate antibodyAnti-Brk Substrate antibodyAnti-STAP2 antibodyAnti-BKS antibody |
Information sourced from Uniprot.org