• Western blot analysis of lysates from Jurkat cells, using STAG3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of Jurkat cells using STAG3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-STAG3 antibody (1161-1210 aa) (STJ95799)

SKU:
STJ95799

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cohesin subunit SA-3 (1161-1210 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAG3
Gene ID: 10734
Uniprot ID: STAG3_HUMAN
Immunogen Region: 1161-1210 aa
Specificity: STAG3 Polyclonal Antibody detects endogenous levels of STAG3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human STAG3 at the amino acid range 1161-1210
Post Translational Modifications Phosphorylated.
Function Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Protein Name Cohesin Subunit Sa-3
Scc3 Homolog 3
Stromal Antigen 3
Stromalin-3
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
Centromere
Associates With Chromatin
In Prophase I Stage Of Meiosis
It Is Found Along The Axial Elements Of Synaptonemal Complexes
In Late-Pachytene-Diplotene
The Bulk Of Protein Dissociates From The Chromosome Arms Probably Because Of Phosphorylation By Plk1
Except At Centromeres
Where Cohesin Complexes Remain
It However Remains Chromatin Associated At The Centromeres Up To Metaphase I
During Anaphase I
It Probably Dissociates From Centromeres
Allowing Chromosomes Segregation
Alternative Antibody Names Anti-Cohesin Subunit Sa-3 antibody
Anti-Scc3 Homolog 3 antibody
Anti-Stromal Antigen 3 antibody
Anti-Stromalin-3 antibody
Anti-STAG3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance