Anti-ST8SIA1 antibody (STJA0007780)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ST8SIA1
General Information
| Short Description | Rabbit polyclonal anti-Alpha-N-acetylneuraminide alpha-2, 8-sialyltransferase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ST8SIA1 |
| Gene ID | 6489 |
| Uniprot ID | SIA8A_HUMAN |
| Immunogen | Synthesized peptide derived from human ST8SIA1 |
| Specificity | This antibody detects endogenous levels of ST8SIA1 at Human, Mouse |
Additional Info
| Function | Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3.gangliosides are a subfamily of complex glycosphingolipds that contain one or more residues of sialic acid. Can catalyze the addition of a second alpha-2,8-sialic acid to GD3 to form GT3. Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively. Can synthesize unusual tetra- and pentasialylated lactosylceramide derivatives identified as GQ3 (II3Neu5Ac4-Gg2Cer) and GP3 (II3Neu5Ac5-Gg2Cer) in breast cancer cells. |
| Protein Name | Alpha-N-Acetylneuraminide Alpha-2 -8-SialyltransferaseAlpha-2 -8-Sialyltransferase 8aGanglioside Gd3 SynthaseGanglioside Gt3 SynthaseSialyltransferase 8aSiat8-ASialyltransferase St8sia ISt8siai |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-N-Acetylneuraminide Alpha-2 -8-Sialyltransferase antibodyAnti-Alpha-2 -8-Sialyltransferase 8a antibodyAnti-Ganglioside Gd3 Synthase antibodyAnti-Ganglioside Gt3 Synthase antibodyAnti-Sialyltransferase 8a antibodyAnti-Siat8-A antibodyAnti-Sialyltransferase St8sia I antibodyAnti-St8siai antibodyAnti-ST8SIA1 antibodyAnti-SIAT8 antibodyAnti-SIAT8A antibody |
Information sourced from Uniprot.org