Anti-ST3GAL6 antibody (STJA0008300)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ST3GAL6
General Information
| Short Description | Rabbit polyclonal anti-Type 2 lactosamine alpha-2, 3-sialyltransferase for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ST3GAL6 |
| Gene ID | 10402 |
| Uniprot ID | SIA10_HUMAN |
| Immunogen | Synthesized peptide derived from human ST3GAL6 |
| Specificity | This antibody detects endogenous levels of ST3GAL6 at Human, Mouse, Rat |
Additional Info
| Function | Transfers the sialyl residue from CMP-N-acetyl-beta-neuraminate to the terminal galactose residue on sugar chains of glycoproteins and glycolipids. It's alpha-2,3-sialyltransferase activity is specific toward type II glycan chains (Galbeta1-4GlcNAc) on glycoproteins and glycolipids such as neolactosides nLc4Cer and nLc6Cer, whose sialyl-products serve as precursors for the Lewis X antigen. Critically involved in the synthesis of functional selectin ligands needed for neutrophil recruitment during inflammation and lymphocyte homing to the lymph nodes. |
| Protein Name | Type 2 Lactosamine Alpha-2 -3-SialyltransferaseCmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase ViSt3gal ViSt3galviSialyltransferase 10 |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-2022854Reactome: R-HSA-4085001Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Type 2 Lactosamine Alpha-2 -3-Sialyltransferase antibodyAnti-Cmp-Neuac -Beta-Galactoside Alpha-2 -3-Sialyltransferase Vi antibodyAnti-St3gal Vi antibodyAnti-St3galvi antibodyAnti-Sialyltransferase 10 antibodyAnti-ST3GAL6 antibodyAnti-SIAT10 antibody |
Information sourced from Uniprot.org