Anti-SSX-SS18 antibody [ZR463] (STJ180683)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized SS18-SSX fusion protein
General Information
| Short Description | Rabbit monoclonal SSX-SS18 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR463 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | L1RE1Uniprot ID=LORF1_HUMAN" |
| Immunogen | Synthesized SS18-SSX fusion protein |
| Specificity | Positive Control: Synovial sarcoma |
Additional Info
| Post Translational Modifications | Polyubiquitinated, probably by UBR2, which induces its degradation. |
| Function | Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded. |
| Protein Name | Line-1 Retrotransposable Element Orf1 ProteinL1orf1pLine Retrotransposable Element 1Line1 Retrotransposable Element 1 |
| Cellular Localisation | NucleusNucleolusCytoplasmCytoplasmic Ribonucleoprotein GranuleStress GranuleColocalizes With Its Encoding Rna In Cytoplasmic Ribonucleoprotein ParticleMainly CytoplasmicRarely Detected In The NucleusPossibly Within The Nucleolus |
| Alternative Antibody Names | Anti-Line-1 Retrotransposable Element Orf1 Protein antibodyAnti-L1orf1p antibodyAnti-Line Retrotransposable Element 1 antibodyAnti-Line1 Retrotransposable Element 1 antibodyAnti-L1RE1 antibodyAnti-LRE1 antibody |
Information sourced from Uniprot.org